The Artemis K-101 has been designed for optimum performance with CISbio´s HTRF^® reagents. The HTRF^® approved instrument is extremely easy to use and guarantees superior performance even with demanding applications.

Dedicated Optics

The internal reflection epi-fluorescence optics paired with selected excitation and emission filters and a sensitive detector operated in single photon counting mode ensures best performance with low background and high sensitivity comparable to laser-based systems.

HTRF^® compatible

The instrument has been validated for all of CISbio´s HTRF^® reagents. Any HTRF^® assay based on either the Europium or the new Terbium cryptates can be measured with superior performance. The HTRF^® assay platform from CISbio offers the researchers a highly sensitive, robust technology for the detection of biological interactions such as G-Protein Coupled Receptor (GPCR), kinase and imflammation biomarkers among others.

Easy-to-use software

The Artemis is completely controlled by the MicroPlateReader software package. The user is able to adjust the numbers of flashes and thus the respective reading times per well and plate. The HTRF^® ratio calculation derived from the donor and acceptor signals, a patented method to correct for quenching and sample interferences, is automatically performed. Even standard curves can be calculated with the software.

Specifications:

• Measurement technology: HTRF^®
• Light source: High energy Xenon flash lamp
• Detection System: Single photon counting PMT, 620 and 665 nm filters, sequential measurement
• Plate formats: 96 and 384 well
• Dynamic range: > 2000 % dF high std
• Sensitivity: < 10 pg/mL TNFα
• Reading time: 150 s (96 well, 20 flashes)
• Software incl. HTRF^® ratio calculation
• Interface: USB 2.0
• Power supply: 100/110/240 VAC; 50/60 Hz max. 200 VA
• Dimensions: 440 mm(W) x 450 mm(D) x 250 mm (H)
• Weight: 16 Kg
• Certifications: CE; HTRF^® compatible

HTRF^® is a trademark of CIS bio.
The fluorescence ratio is a correction method developed by CIS bio international with an application limited to the use of HTRF^® reagents and technology, and for which CIS bio international has granted a licence to Berthold. The method is covered by the US patent 5,527,684 and its foreign equivalents.