The LumiBIS is a fully automated imaging system for a wide range of samples stained with fluorescent and colorimetric (visible) dyes.
The system is equipped with a high resolution and sensitive CCD camera.
The LumiBIS features an unique Dark Chamber technology with an automated UV protection mechanism.

Camera

The LumiBIS captures the sharpest possible images with precise sample separation - thanks to its powerful CCD camera with high resolution.
Two different models are available, 1.4 and 2 Mpixels.
The high speed zoom lens results in enhanced sensitivity, collecting maximum light from the sample, while maintaining sharp images.

Featuring a motorized zoom, iris and autofocus, the LumiBIS is a fully automated system.

The unique dark chamber with an automated UV protection mechanism ensures maximum safety.

Illumination

The LumiBIS is equipped with a built-in transilluminator with dual UV/WL illumination and 2 interchangeable UV and WL drawers. Automatic Drawer Detection technology indentifies the type of drawer in use and adjusts the software settings accordingly.
The motorized 6-position filter wheel is equipped with 3 filters in orange, green and red. A WL epi illumination is installed, a UV epi illlumination can be addded optionally.
The optional QuattroLED system provides illumination of 4 different wavelengths at 470nm, 525nm, 620nm and 740nm.


Applications

The LumiBIS has extensive illumination options allowing researchers to document a wide range of samples. With trans and epi illumination sources, six-position filter wheel and an unique LEDs System (QuattroLED System), you can use this system for almost any fluorescent or colorimetric application.

• Detection and quantitation of nucleic acid and protein stains and labels including: Ethidium Bromide, SYBR™ Green, GelStar™, Fluorescein, Coomassie Brilliant Blue, SYPRO™ Orange, SYPRO™ Red, Silver Stain, SYPRO™ Ruby, Deep Purple™ and many more
• Detection of advanced fluorescent molecules, including Cy2™, Cy3™, Pro-Q™ Diamond, Deep Purple™, Rhodamine Red™ and more
• Other Biological Methods: TLC plates, Dot and slot blots, Autoradiographs, Microplate, Macroarrays, Membranes and more 

Software

The LumiBIS will be delivered standardly with two software packages, GelCapture for imaging acquisition and GelQuant for image analysis.

GelCapture offers complete, automatic control of configuring, capturing, and saving sample images for analysis. GelCapture offers all important image settings adjustable as illumination, focus, brightness, binning and many more. 

The GelQuant software from the TotalLab range enables fast and consistent analysis of your gel images with high levels of automation and accuracy.
You can perform a complete analysis with a single click and then refine results afterwards, or step through the different analysis stages giving you complete control at each stage.
Automated lane creation, band detection and background subtraction are all performed without any user intervention for the utmost in analysis consistency. Molecular weight can be calculated for your bands from the standard marker lane you included on the gel. Classical commercial standards are available in the software or you can create and save your own. The GelQuant software performs precise band edge detection and subtraction of background material which is vital for correct quantitation or normalisation of band material. There are additional tools to adjust band edges and account for band "grimacing" on awkward gels.

Also upgrade with the following modules is possible:

• Array, dot / slot blot analysis
• Colony counting
• A toolbox for general image analysis

Specifications

Camera and Optics
 
CCD resolution:1360(H) x 1024(V); 1.4 Mpixels 
                 or 1600(H) x 1200(V); 2 Mpixels
Gradation: 16 bit file format
Dynamic range: 3.4 orders of magnitude 
Super bright lens: F/1.2, 8-48mm
 
Illumination and Darkroom
 
Dark chamber: automated UV protection mechanism 
Emission filters: 6 position filter wheel with 3 filters included as a standard
Illumination modes: Trans-UV, Trans-WL, Epi-WL
                           optional: Epi-UV
Excitation sources: White Light source, 312nm
                           optional: 254nm, 365nm
                           optional: dual UV source
                           optional: Monochromatic LEDs system (Quattro LED System)
Software
 
Image capture: GelCapture, lifetime free upgrade 
Image analysis: GelQuant for 1D analysis (TotalLab)
                      optional: Phoretix 1D, Phoretix 1D Pro

The MiniBIS and MiniBIS Pro products are available in Germany, The Netherlands, Belgium, Luxemburg, Italy, India, France, Switzerland, UK, Japan and USA.

For other countries please see the DNR Imaging Systems homepage.