Combination of BRET and FRET

The Scientist reports about new nanoparticles that apply BRET (bioluminescence resonance energy transfer) and FRET (fluorescence resonanace energy transfer) for their use in in vivo imaging.

As the signal is created by a luminescence reaction there is low background in the system and the conversion into a near-infrared emission reduces absorption and scattering by the tissue.


Read more at The Scientist