Bioanalytic18.11.2013

Protein-Protein Interactions in Drug Discovery

PPIs represent a major target in drug discovery. Estimations reach up to half a Million of interactions in humans. Mark Wade comments on challenges and solutions of assay design and read-out with special emphasis on BiFC (bi-moilecular fluorescence complementation) and BiLC (bi-molecular luminescence complementation) methods.

Read the entire article in European Pharmaceutical Review